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Rabbit Anti-STXBP3 Recombinant Antibody (BA0105) (CBMAB-0858CQ)

This product is a rabbit antibody that recognizes STXBP3. The antibody BA0105 can be used for immunoassay techniques such as: FC, WB.
See all STXBP3 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
BA0105
Antibody Isotype
IgG
Application
FC, WB

Basic Information

Immunogen
Human Munc18c aa 150-250
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SYNTAXIN BINDING PROTEIN 3
Introduction
STXBP3 (Syntaxin Binding Protein 3) is a Protein Coding gene.Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Entrez Gene ID
6814
UniProt ID
O00186
Alternative Names
PSP; MUNC18C; UNC-18C; MUNC18-3
Function
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Biological Process
Biological Process brain developmentIEA:Ensembl
Biological Process cellular glucose homeostasisIEA:Ensembl
Biological Process cellular response to interferon-gammaIEA:Ensembl
Biological Process insulin secretionIEA:Ensembl
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of calcium ion-dependent exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of glucose importIEA:Ensembl
Biological Process neurotransmitter secretionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neutrophil degranulationManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process platelet aggregationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein to membrane dockingIEA:Ensembl
Biological Process response to insulinIEA:Ensembl
Biological Process vesicle docking involved in exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm, cytosol
Cell membrane
In platelets, predominantly cytosolic. Low amounts membrane-associated.
PTM
Phosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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