Rabbit Anti-STXBP3 Recombinant Antibody (BA0105) (CBMAB-0858CQ)

Name: Rabbit Anti-STXBP3 Recombinant Antibody (BA0105)
SKU: CBMAB-0858CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

BA0105

Application

FC, WB

Immunogen

Human Munc18c aa 150-250

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SYNTAXIN BINDING PROTEIN 3

Introduction

STXBP3 (Syntaxin Binding Protein 3) is a Protein Coding gene.Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.

Entrez Gene ID

6814

UniProt ID

O00186

Alternative Names

PSP; MUNC18C; UNC-18C; MUNC18-3

Function

Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.

Biological Process

Biological Process brain developmentIEA:Ensembl
Biological Process cellular glucose homeostasisIEA:Ensembl
Biological Process cellular response to interferon-gammaIEA:Ensembl
Biological Process insulin secretionIEA:Ensembl
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of calcium ion-dependent exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of glucose importIEA:Ensembl
Biological Process neurotransmitter secretionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neutrophil degranulationManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process platelet aggregationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein to membrane dockingIEA:Ensembl
Biological Process response to insulinIEA:Ensembl
Biological Process vesicle docking involved in exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm, cytosol
Cell membrane
In platelets, predominantly cytosolic. Low amounts membrane-associated.

PTM

Phosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Rabbit Anti-STXBP3 Recombinant Antibody (BA0106) (CAT#: CBMAB-0859CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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