Human Recombinant STXBP3 protein, GST Tag (V2LY-0526-LY5664)

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Basic Information

Expressed Host
Baculovirus-Insect Cells
Protein Species
Human
Tag
GST Tag
Protein Construction
This product is Human Recombinant STXBP3 protein, GST Tag consist of Amino Acid: 1-592 and predicts a molecular mass of 95.6 kDa.
Molecule Mass
95.6 kDa
Sequence
Amino Acid: 1-592
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>82% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile Tris, NaCl, Glutathione, EDTA, DTT, PMSF, Glycerol
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
SYNTAXIN BINDING PROTEIN 3
Function
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Biological Process
Biological Process brain developmentIEA:Ensembl
Biological Process cellular glucose homeostasisIEA:Ensembl
Biological Process cellular response to interferon-gammaIEA:Ensembl
Biological Process insulin secretionIEA:Ensembl
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of calcium ion-dependent exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of glucose importIEA:Ensembl
Biological Process neurotransmitter secretionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neutrophil degranulationManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process platelet aggregationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein to membrane dockingIEA:Ensembl
Biological Process response to insulinIEA:Ensembl
Biological Process vesicle docking involved in exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm, cytosol
Cell membrane
In platelets, predominantly cytosolic. Low amounts membrane-associated.
PTM
Phosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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