Mouse Anti-SUGT1 Recombinant Antibody (CBXS-2045) (CBMAB-S4812-CQ)

Name: Mouse Anti-SUGT1 Recombinant Antibody (CBXS-2045)
SKU: CBMAB-S4812-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-2045

Application

WB, IP, IF, ELISA

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SUGT1

Introduction

This gene encodes a highly conserved nuclear protein involved in kinetochore function and required for the G1/S and G2/M transitions. This protein interacts with heat shock protein 90. Alternative splicing results in multiple transcript variants. Pseudogenes for this gene have been defined on several different chromosomes.

Entrez Gene ID

10910

UniProt ID

Q9Y2Z0

Alternative Names

SGT1

Function

May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.

Biological Process

Biological Process mitotic cell cycleManual Assertion Based On ExperimentTAS:ProtInc
Biological Process protein stabilizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of protein stabilityManual Assertion Based On ExperimentIDA:AgBase

Cellular Location

Cytoplasm
Nucleus
Translocates to the nucleus upon heat shock, requiring S100A6.

PTM

Phosphorylated at Ser-281 and Ser-331, dephosphorylation promotes nuclear translocation, most likely due to disruption of the SUGT1-HSP90 complex.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

SUGT1 Matched Antibody Pair (1167) (CAT#: APMAB-1167LY)

SUGT1 Matched Antibody Pair (1168) (CAT#: APMAB-1168LY)

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SUGT1 Matched Antibody Pair (1167) (CAT#: APMAB-1167LY)

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Mouse Anti-SUGT1 Recombinant Antibody (CBXS-3381) (CAT#: CBMAB-S6116-CQ)

Mouse Anti-SUGT1 Recombinant Antibody (CBXS-2059) (CAT#: CBMAB-S4826-CQ)

Mouse Anti-SUGT1 Recombinant Antibody (CBXS-3792) (CAT#: CBMAB-S1063-CQ)

Mouse Anti-SUGT1 Recombinant Antibody (1A10) (CAT#: CBMAB-A8763-LY)

SUGT1 Matched Antibody Pair (1168) (CAT#: APMAB-1168LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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