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SUGT1

This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Full Name
SUGT1
Function
May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.
Biological Process
Biological Process mitotic cell cycleManual Assertion Based On ExperimentTAS:ProtInc
Biological Process protein stabilizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of protein stabilityManual Assertion Based On ExperimentIDA:AgBase
Cellular Location
Cytoplasm
Nucleus
Translocates to the nucleus upon heat shock, requiring S100A6.
PTM
Phosphorylated at Ser-281 and Ser-331, dephosphorylation promotes nuclear translocation, most likely due to disruption of the SUGT1-HSP90 complex.
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Anti-SUGT1 antibodies

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Mouse Anti-SUGT1 Recombinant Antibody (6G5) (CBMAB-A8764-LY)

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Target: SUGT1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human, Mouse, Rat
Clone: 6G5
Application*: WB, E
Datasheet SDS

Mouse Anti-SUGT1 Recombinant Antibody (1A10) (CBMAB-A8763-LY)

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Target: SUGT1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 1A10
Application*: WB, E
Datasheet SDS

Mouse Anti-SUGT1 Recombinant Antibody (CBXS-3381) (CBMAB-S6116-CQ)

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Target: SUGT1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: CBXS-3381
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-SUGT1 Recombinant Antibody (CBXS-2059) (CBMAB-S4826-CQ)

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Target: SUGT1
Host: Mouse
Specificity: Human
Clone: CBXS-2059
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-SUGT1 Recombinant Antibody (CBXS-2045) (CBMAB-S4812-CQ)

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Target: SUGT1
Host: Mouse
Specificity: Human
Clone: CBXS-2045
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-SUGT1 Recombinant Antibody (CBXS-0840) (CBMAB-S3764-CQ)

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Target: SUGT1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: CBXS-0840
Application*: SE, E, WB, IF
Datasheet SDS

Mouse Anti-SUGT1 Recombinant Antibody (CBXS-3792) (CBMAB-S1063-CQ)

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Target: SUGT1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human, Mouse, Rat
Clone: CBXS-3792
Application*: E, IP, WB
Datasheet SDS

SUGT1 Matched Antibody Pair (1168) (APMAB-1168LY)

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Target: SUGT1
Specificity: Human
Datasheet SDS

SUGT1 Matched Antibody Pair (1167) (APMAB-1167LY)

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Target: SUGT1
Specificity: Human
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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