SUGT1

This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Full Name

SUGT1

Function

May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.

Biological Process

Biological Process mitotic cell cycleManual Assertion Based On ExperimentTAS:ProtInc
Biological Process protein stabilizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of protein stabilityManual Assertion Based On ExperimentIDA:AgBase

Cellular Location

Cytoplasm
Nucleus
Translocates to the nucleus upon heat shock, requiring S100A6.

PTM

Phosphorylated at Ser-281 and Ser-331, dephosphorylation promotes nuclear translocation, most likely due to disruption of the SUGT1-HSP90 complex.

Anti-SUGT1 antibodies

Mouse Anti-SUGT1 Recombinant Antibody (CBXS-3381) (CBMAB-S6116-CQ)

Datasheet

SDS

Target: SUGT1

Host: Mouse

Antibody Isotype: IgG3, κ

Specificity: Human

Clone: CBXS-3381

Application*: E, IF, WB

Mouse Anti-SUGT1 Recombinant Antibody (CBXS-2059) (CBMAB-S4826-CQ)

Datasheet

SDS

Target: SUGT1

Host: Mouse

Specificity: Human

Clone: CBXS-2059

Application*: WB, IP, IF, E

Datasheet

SDS

Target: SUGT1

Specificity: Human

SUGT1 Matched Antibody Pair (1167) (APMAB-1167LY)

Datasheet

SDS

Target: SUGT1

Specificity: Human

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)