Mouse Anti-SULT2A1 Recombinant Antibody (4D7) (CBMAB-C6807-LY)

Name: Mouse Anti-SULT2A1 Recombinant Antibody (4D7)
SKU: CBMAB-C6807-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

4D7

Application

WB, FC, ICC/IF

Immunogen

Full length human recombinant protein of human SULT2A1 (NP_003158) produced in HEK293T cell

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

SULT2A1

Entrez Gene ID

6822

UniProt ID

Q06520

Function

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups (PubMed:7678732, PubMed:2268288, PubMed:14573603, PubMed:18042734, PubMed:19589875, PubMed:21187059, PubMed:29671343, PubMed:7854148).
Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis (PubMed:21187059, PubMed:19589875, PubMed:14573603).
Plays a key role in bile acid metabolism (PubMed:2268288).
In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols (By similarity).

Biological Process

Biological Process 3'-phosphoadenosine 5'-phosphosulfate metabolic processManual Assertion Based On ExperimentIDA:CAFA
Biological Process bile acid catabolic processIEA:UniProtKB-KW
Biological Process cholesterol metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ethanol catabolic processManual Assertion Based On ExperimentIDA:CAFA
Biological Process lipid catabolic processIEA:UniProtKB-KW
Biological Process steroid metabolic processManual Assertion Based On ExperimentIDA:GO_Central
Biological Process sulfationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process thyroid hormone metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process xenobiotic metabolic processManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cytoplasm

PTM

The N-terminus is blocked.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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