Rabbit Anti-SUZ12 Recombinant Antibody (
1B10) (V2LY-0725-LY978)
Compare
Online Inquiry
Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate, HL60 whole cell lysate, THP-1 whole cell lysate, K562 whole cell lysate
All lanes: SUZ12 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 84 kDa
Observed band size: 90 kDa
Lane 1: Rabbit control IgG instead of V2LY-0725-LY978 in K562 whole cell lysate.
For western blotting,a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
Lane 2: V2LY-0725-LY978(2µg)+ K562 whole cell lysate(500µg)
Lane 3: K562 whole cell lysate (10µg)
Basic Information
| Application | Note |
| WB | 1:500-1:5,000 |
| IHC | 1:50-1:200 |
| IP | 1:200-1:1,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
The PRC2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (PubMed:12435631, PubMed:12351676, PubMed:15385962, PubMed:15099518, PubMed:15225548, PubMed:15684044, PubMed:16431907, PubMed:18086877, PubMed:18285464).
Genes repressed by the PRC2 complex include HOXC8, HOXA9, MYT1 and CDKN2A (PubMed:15231737, PubMed:16618801, PubMed:17200670, PubMed:31959557).
Biological Process dosage compensation by inactivation of X chromosomeIEA:Ensembl
Biological Process histone ubiquitinationIEA:Ensembl
Biological Process negative regulation of cell differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process oligodendrocyte differentiationIEA:Ensembl
Biological Process positive regulation of cell population proliferationIEA:Ensembl
Localizes to chromatin as part of the PRC2 complex.
An autosomal dominant syndrome characterized by generalized overgrowth, dysmorphic features, musculoskeletal abnormalities, developmental delay and intellectual disability. Some patients have genitourinary and structural brain abnormalities.
1B10)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon
$30 eGift Card
Submit a review
Loading...
Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Related Products
Mouse Anti-SUZ12 Recombinant Antibody (CBXS-3465) (CAT#: CBMAB-S6196-CQ)
Mouse Anti-SUZ12 Recombinant Antibody (CBXS-4827) (CAT#: CBMAB-S2051-CQ)
Mouse Anti-SUZ12 Recombinant Antibody (SUZ220A) (CAT#: CBMAB-S6644-CQ)
Mouse Anti-SUZ12 Recombinant Antibody (2B12-B4-C0) (CAT#: CBMAB-Z0293-LY)
Mouse Anti-SUZ12 Recombinant Antibody (CBXS-5802) (CAT#: CBMAB-S0659-CQ)
Mouse Anti-SUZ12 Recombinant Antibody (CBXS-2479) (CAT#: CBMAB-S5236-CQ)
Mouse Anti-SUZ12 Recombinant Antibody (CBT3113) (CAT#: V2LY-0625-LY559)
Mouse Anti-SUZ12 Recombinant Antibody (CBT1173) (CAT#: V2LY-0625-LY2973)
Mouse Anti-SUZ12 Recombinant Antibody (CBT4186) (CAT#: V2LY-0625-LY558)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
Online InquiryContact us
