Mouse Anti-SYCP3 Recombinant Antibody (CBT1124) (V2LY-0625-LY3017)
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Basic Information
| Application | Note |
| WB | 1:1,000-1:2,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Required for normal meiosis during spermatogenesis and male fertility (PubMed:14643120).
Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).
Biological Process male meiosis INAS:UniProtKB1 Publication
Biological Process meiotic cell cycleIBA:GO_Central1 Publication
Biological Process spermatid developmentIBA:GO_Central1 Publication
Biological Process spermatogenesis, exchange of chromosomal proteinsIMP:UniProtKB1 Publication
Chromosome
Chromosome, centromere
It is present in early unpaired cores, in the lateral domains of the synaptonemal complex and in the chromosome cores when they separate at diplotene. It is found axial to the metaphase I chromosomes and in association with pairs of sister centromeres. The centromere-associated protein becomes dissociated from the centromeres at anaphase II and is not found in mitotic metaphase centromeres.
An infertility disorder characterized by azoospermia, a condition of having no sperm present in the ejaculate. Testicular histology shows arrest of spermatogenesis at the pachytene stage of primary spermatocytes.
Pregnancy loss, recurrent, 4 (RPRGL4):
A common complication of pregnancy, resulting in spontaneous abortion before the fetus has reached viability. The term includes all miscarriages from the time of conception until 24 weeks of gestation. Recurrent pregnancy loss is defined as 3 or more consecutive spontaneous abortions.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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