Mouse Anti-SYT4 Recombinant Antibody (CBXS-5061) (CBMAB-S2282-CQ)

Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Involved in neuronal dense core vesicles (DCVs) mobility through its interaction with KIF1A. Upon increased neuronal activity, phosphorylation by MAPK8/JNK1 destabilizes the interaction with KIF1A and captures DCVs to synapses (By similarity).
Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process cellular response to calcium ionIBA:GO_Central1 Publication
Biological Process dense core granule cytoskeletal transportISS:UniProtKB
Biological Process memoryIEA:Ensembl
Biological Process negative regulation of calcium ion-dependent exocytosisNAS:ParkinsonsUK-UCL1 Publication
Biological Process negative regulation of catecholamine secretionIGI:ParkinsonsUK-UCL1 Publication
Biological Process negative regulation of protein secretionIEA:Ensembl
Biological Process negative regulation of retrograde trans-synaptic signaling by neuropeptideIEA:Ensembl
Biological Process negative regulation of short-term neuronal synaptic plasticityIEA:Ensembl
Biological Process negative regulation of synaptic vesicle exocytosisIEA:Ensembl
Biological Process neurotransmitter secretionIEA:Ensembl
Biological Process positive regulation of calcium ion-dependent exocytosisNAS:ParkinsonsUK-UCL1 Publication
Biological Process positive regulation of dendrite extensionIDA:UniProtKB1 Publication
Biological Process positive regulation of dense core granule exocytosisIEA:Ensembl
Biological Process positive regulation of glutamate secretionIEA:Ensembl
Biological Process regulation of calcium ion-dependent exocytosisIBA:GO_Central1 Publication
Biological Process regulation of dopamine secretionIBA:GO_Central1 Publication
Biological Process regulation of endocytosisIEA:Ensembl
Biological Process regulation of presynaptic dense core granule exocytosisIEA:Ensembl
Biological Process regulation of vesicle fusionIEA:Ensembl
Biological Process trans-synaptic signaling by BDNF, modulating synaptic transmissionIEA:Ensembl
Biological Process vesicle fusionIBA:GO_Central1 Publication
Biological Process vesicle-mediated transportIBA:GO_Central1 Publication
Helical: 17-37
Cytoplasmic: 38-425
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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