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Mouse Anti-TACC2 Recombinant Antibody (CBYJT-1777) (CBMAB-T0838-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TACC2 (Transforming Acidic Coiled-Coil Containing Protein 2). The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all TACC2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat, Mouse
Clone
CBYJT-1777
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 2294-2421 mapping near the C-terminus of TACC2 of human origin
Specificity
Human, Rat, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 2294-2421

Target

Full Name
Transforming Acidic Coiled-Coil Containing Protein 2
Introduction
TACC2 plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. It is Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). It may function in organizing centrosomal microtubules. It may act as a tumor suppressor protein. It may represent a tumor progression marker.
Entrez Gene ID
Human10579
Mouse57752
Rat309025
UniProt ID
HumanO95359
MouseQ9JJG0
RatD3ZXK3
Alternative Names
AZU-1; ECTACC
Function
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity).
May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker.
Biological Process
Biological Process cell population proliferationIBA:GO_Central1 Publication
Biological Process cerebral cortex developmentIBA:GO_Central1 Publication
Biological Process microtubule cytoskeleton organizationIBA:GO_Central1 Publication
Biological Process mitotic spindle organizationIEA:InterPro
Cellular Location
Cytoplasm
Nucleus
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
PTM
Phosphorylated by TTK; which is required for localization in centrosome.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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