TACC2
TACC2 plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. It is Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). It may function in organizing centrosomal microtubules. It may act as a tumor suppressor protein. It may represent a tumor progression marker.
Full Name
Transforming Acidic Coiled-Coil Containing Protein 2
Function
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity).
May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker.
May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker.
Biological Process
Biological Process cell population proliferationIBA:GO_Central1 Publication
Biological Process cerebral cortex developmentIBA:GO_Central1 Publication
Biological Process microtubule cytoskeleton organizationIBA:GO_Central1 Publication
Biological Process mitotic spindle organizationIEA:InterPro
Biological Process cerebral cortex developmentIBA:GO_Central1 Publication
Biological Process microtubule cytoskeleton organizationIBA:GO_Central1 Publication
Biological Process mitotic spindle organizationIEA:InterPro
Cellular Location
Cytoplasm
Nucleus
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Nucleus
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
PTM
Phosphorylated by TTK; which is required for localization in centrosome.
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Anti-TACC2 antibodies
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Target: TACC2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-1777
Application*: WB, IP, IF, E
Target: TACC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1776
Application*: WB
Target: TACC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1775
Application*: WB
Target: TACC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1774
Application*: P, WB
Target: TACC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1773
Application*: P, WB
Target: TACC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1772
Application*: WB
Target: TACC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1771
Application*: WB
Target: TACC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1770
Application*: WB
Target: TACC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1769
Application*: WB
Target: TACC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1768
Application*: WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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