Mouse Anti-TAX1BP1 Monoclonal Antibody (1D4) (CBMAB-0220-LY)

Name: Mouse Anti-TAX1BP1 Monoclonal Antibody (1D4)
SKU: CBMAB-0220-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1D4

Application

IP, MA

Immunogen

Recombinant peptide (aa 1-529)

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

TAX1BP1 Gene(Protein Coding) Tax1 Binding Protein 1

Introduction

This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.

Entrez Gene ID

8887

UniProt ID

Q86VP1

Alternative Names

CALCOCO3; TXBP151

Function

Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.

Biological Process

Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process negative regulation of apoptotic processIBA:GO_Central1 Publication
Biological Process negative regulation of NF-kappaB transcription factor activityISS:BHF-UCL

Cellular Location

cytosol
extracellular exosome

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

TAX1BP1 Matched Antibody Pair (1185) (CAT#: APMAB-1185LY)

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Mouse Anti-TAX1BP1 Recombinant Antibody (CBYJT-2022) (CAT#: CBMAB-T1115-YJ)

Mouse Anti-TAX1BP1 Monoclonal Antibody (1D8) (CAT#: CBMAB-0221-LY)

Mouse Anti-TAX1BP1 Recombinant Antibody (CBYJT-2019) (CAT#: CBMAB-T1112-YJ)

Mouse Anti-TAX1BP1 Recombinant Antibody (CBYJT-2018) (CAT#: CBMAB-T1110-YJ)

TAX1BP1 Matched Antibody Pair (1185) (CAT#: APMAB-1185LY)

Rabbit Anti-TAX1BP1 Recombinant Antibody (CBYJT-2020) (CAT#: CBMAB-T1113-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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