TAX1BP1

This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
Full Name
TAX1BP1 Gene(Protein Coding) Tax1 Binding Protein 1
Function
Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.
Biological Process
Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process negative regulation of apoptotic processIBA:GO_Central1 Publication
Biological Process negative regulation of NF-kappaB transcription factor activityISS:BHF-UCL
Cellular Location
cytosol
extracellular exosome
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Anti-TAX1BP1 antibodies

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Rabbit Anti-TAX1BP1 Recombinant Antibody (D1D5) (CBMAB-CP2701-LY)

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Target: TAX1BP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D1D5
Application*: WB, IP
Datasheet SDS

Mouse Anti-TAX1BP1 Recombinant Antibody (CBYJT-2022) (CBMAB-T1115-YJ)

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Target: TAX1BP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-2022
Application*: WB, SE, E
Datasheet SDS

Mouse Anti-TAX1BP1 Recombinant Antibody (CBYJT-2021) (CBMAB-T1114-YJ)

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Target: TAX1BP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-2021
Application*: SE, E, WB
Datasheet SDS

Rabbit Anti-TAX1BP1 Recombinant Antibody (CBYJT-2020) (CBMAB-T1113-YJ)

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Target: TAX1BP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-2020
Application*: WB, IP
Datasheet SDS

Mouse Anti-TAX1BP1 Recombinant Antibody (CBYJT-2019) (CBMAB-T1112-YJ)

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Target: TAX1BP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-2019
Application*: WB
Datasheet SDS

Mouse Anti-TAX1BP1 Recombinant Antibody (3098C2a) (CBMAB-T1111-YJ)

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Target: TAX1BP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3098C2a
Application*: DB, WB
Datasheet SDS

Mouse Anti-TAX1BP1 Recombinant Antibody (CBYJT-2018) (CBMAB-T1110-YJ)

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Target: TAX1BP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-2018
Application*: E, WB
Datasheet SDS

Mouse Anti-TAX1BP1 Monoclonal Antibody (1D8) (CBMAB-0221-LY)

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Target: TAX1BP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1D8
Application*: IP, M
Datasheet SDS

Mouse Anti-TAX1BP1 Monoclonal Antibody (1D4) (CBMAB-0220-LY)

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Target: TAX1BP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1D4
Application*: IP, M
Datasheet SDS

TAX1BP1 Matched Antibody Pair (1185) (APMAB-1185LY)

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Target: TAX1BP1
Specificity: Human
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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