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Rabbit Anti-TAX1BP1 Recombinant Antibody (CBYJT-2020) (CBMAB-T1113-YJ)

Provided herein is a Rabbit monoclonal antibody, which binds to TAX1BP1 (Tax1 Binding Protein 1). The antibody can be used for immunoassay techniques, such as WB, IP.
See all TAX1BP1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBYJT-2020
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TAX1BP1 Gene(Protein Coding) Tax1 Binding Protein 1
Introduction
TAX1BP1 is a HTLV-1 tax1 binding protein. TAX1BP1 interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. TAX1BP1 may also have a role in the inhibition of inflammatory signaling pathways.
Entrez Gene ID
UniProt ID
Alternative Names
Tax1 Binding Protein 1; Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 1; TRAF6-Binding Protein; T6BP; Tax1-Binding Protein 1; CALCOCO3; TXBP151
Function
Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.
Biological Process
Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process negative regulation of apoptotic processIBA:GO_Central1 Publication
Biological Process negative regulation of NF-kappaB transcription factor activityISS:BHF-UCL
Cellular Location
cytosol
extracellular exosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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