Mouse Anti-TBX18 Recombinant Antibody (3D9) (CBMAB-A8905-LY)

Name: Mouse Anti-TBX18 Recombinant Antibody (3D9)
SKU: CBMAB-A8905-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3D9

Application

WB, ELISA

Immunogen

TBX18 (XP_496819, 454 a.a. ~ 560 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

T-Box 18

Entrez Gene ID

Human	9096
Mouse	76365
Rat	315870

UniProt ID

Human	O95935
Mouse	Q9EPZ6
Rat	D4A1V6

Function

Acts as transcriptional repressor involved in developmental processes of a variety of tissues and organs, including the heart and coronary vessels, the ureter and the vertebral column. Required for embryonic development of the sino atrial node (SAN) head area.

Biological Process

Biological Process cell fate specificationIBA:GO_Central1 Publication
Biological Process cochlea morphogenesisISS:ARUK-UCL
Biological Process morphogenesis of embryonic epitheliumIBA:GO_Central1 Publication
Biological Process negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formationISS:BHF-UCL
Biological Process positive regulation of DNA-templated transcriptionIEA:InterPro
Biological Process regulation of SA node cell action potentialIMP:BHF-UCL1 Publication
Biological Process regulation of transcription by RNA polymerase IIIBA:GO_Central1 Publication
Biological Process sinoatrial node cell developmentIMP:BHF-UCL1 Publication
Biological Process sinoatrial node cell fate commitmentIMP:BHF-UCL1 Publication
Biological Process sinoatrial node developmentISS:BHF-UCL
Biological Process smooth muscle cell differentiationISS:ARUK-UCL
Biological Process somitogenesisISS:ARUK-UCL
Biological Process ureter developmentIMP:UniProtKB1 Publication

Cellular Location

Nucleus

Involvement in disease

Congenital anomalies of kidney and urinary tract 2 (CAKUT2):
A disorder encompassing a broad spectrum of renal and urinary tract malformations that include renal agenesis, kidney hypodysplasia, multicystic kidney dysplasia, duplex collecting system, posterior urethral valves and ureter abnormalities. Congenital anomalies of kidney and urinary tract are the commonest cause of chronic kidney disease in children.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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