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Mouse Anti-SOHLH2 Recombinant Antibody (1E1) (CBMAB-A8994-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1E1
Antibody Isotype
IgG2a, κ
Application
IP, ELISA

Basic Information

Immunogen
TEB1 (AAH25383, 1 a.a. ~ 225 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Spermatogenesis And Oogenesis Specific Basic Helix-Loop-Helix 2
Entrez Gene ID
54937
UniProt ID
Q9NX45
Alternative Names
FLJ20449; TEB1; bA121N13.2
Function
Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I (By similarity).
Biological Process
Biological Process cell differentiationISS:UniProtKB
Biological Process oocyte differentiationISS:UniProtKB
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process spermatogenesisISS:UniProtKB
Cellular Location
Nucleus
Cytoplasm
Translocates from the cytoplasm into the nucleus and the translocation is dependent on SOHLH1 expression.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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