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Mouse Anti-TFAP4 Recombinant Antibody (CBYJT-2639) (CBMAB-T1818-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TFAP4 (Transcription Factor AP-4). The antibody can be used for immunoassay techniques, such as ELISA, ICC, IHC, WB.
See all TFAP4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2639
Antibody Isotype
IgG2a
Application
ELISA, ICC, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 93-193

Target

Full Name
transcription factor AP-4 (activating enhancer binding protein 4)
Introduction
TFAP4 is a transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. TFAP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).
Entrez Gene ID
7023
UniProt ID
Q01664
Alternative Names
Transcription Factor AP-4; Class C Basic Helix-Loop-Helix Protein 41; Activating Enhancer-Binding Protein 4; BHLHc41; Transcription Factor AP-4 (Activating Enhancer-Binding Protein 4); Transcription Factor AP-4 (Activating Enhancer Binding Protein 4); AP-4
Function
Transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence 5'-CAGCTG-3'.
Biological Process
Biological Process cellular response to dexamethasone stimulusSource:Ensembl
Biological Process DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorSource:UniProtKB1 Publication
Biological Process negative regulation by host of viral transcriptionSource:UniProtKB2 Publications
Biological Process negative regulation of cell population proliferationSource:UniProtKB1 Publication
Biological Process negative regulation of cyclin-dependent protein serine/threonine kinase activitySource:UniProtKB1 Publication
Biological Process negative regulation of DNA bindingSource:UniProtKB2 Publications
Biological Process negative regulation of DNA-templated transcriptionSource:UniProtKB3 Publications
Biological Process negative regulation of gene expressionSource:Ensembl
Biological Process positive regulation by host of viral transcriptionSource:UniProtKB1 Publication
Biological Process positive regulation of apoptotic processSource:UniProtKB1 Publication
Biological Process positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwaySource:Ensembl
Biological Process positive regulation of DNA-templated transcriptionSource:UniProtKB1 Publication
Biological Process protein-containing complex assemblySource:UniProtKB1 Publication
Biological Process regulation of mitotic cell cycle phase transitionSource:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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