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Mouse Anti-THAP11 Recombinant Antibody (CBYJT-2901) (CBMAB-T2135-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to THAP11 (THAP Domain Containing 11). The antibody can be used for immunoassay techniques, such as ICC, WB.
See all THAP11 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2901
Antibody Isotype
IgG2a
Application
ICC, WB

Basic Information

Immunogen
Recombinant corresponding to Gly226Met314 in THAP11 expressed in E. coli (Q96EK4)
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 226-314

Target

Full Name
THAP11 Gene(Protein Coding) THAP Domain Containing 11
Introduction
THAP11 contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases.
Entrez Gene ID
57215
UniProt ID
Q96EK4
Alternative Names
THAP Domain Containing 11; THAP Domain-Containing Protein 11; HRIHFB2206; CTG-B43a; CTG-B45d; RONIN
Function
Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity).
Biological Process
Biological Process cell population proliferationSource:Ensembl
Biological Process electron transport chainSource:Ensembl
Biological Process negative regulation of neuron apoptotic processSource:Ensembl
Biological Process negative regulation of transcription by RNA polymerase IISource:NTNU_SB1 Publication
Biological Process neuron differentiationSource:Ensembl
Biological Process positive regulation of androgen receptor activitySource:Ensembl
Biological Process regulation of mitochondrial transcriptionSource:Ensembl
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Cellular Location
Nucleus
Cytoplasm
May be regulated by shuttling of the protein between the cytoplasm and nucleus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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