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Mouse Anti-THAP11 Recombinant Antibody (P56-507) (CBMAB-R4019-CN)

This product is a Mouse antibody that recognizes THAP11. The antibody P56-507 can be used for immunoassay techniques such as: WB, FC, IF.
See all THAP11 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
P56-507
Antibody Isotype
IgG2b, κ
Application
WB, FC, IF

Basic Information

Immunogen
Human Ronin/THAP11 Recombinant Protein
Specificity
Human, Mouse
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
0.5 mg/mL

Target

Full Name
THAP11 Gene(Protein Coding) THAP Domain Containing 11
Introduction
The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human57215
Mouse59016
UniProt ID
HumanQ96EK4
MouseQ9JJD0
Alternative Names
THAP Domain Containing 11; THAP Domain-Containing Protein 11; HRIHFB2206; CTG-B43a; CTG-B45d; RONIN;
Function
Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity).
Biological Process
Biological Process cell population proliferationSource:Ensembl
Biological Process electron transport chainSource:Ensembl
Biological Process negative regulation of neuron apoptotic processSource:Ensembl
Biological Process negative regulation of transcription by RNA polymerase IISource:NTNU_SB1 Publication
Biological Process neuron differentiationSource:Ensembl
Biological Process positive regulation of androgen receptor activitySource:Ensembl
Biological Process regulation of mitochondrial transcriptionSource:Ensembl
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Cellular Location
Nucleus
Cytoplasm
May be regulated by shuttling of the protein between the cytoplasm and nucleus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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