Mouse Anti-THPO Recombinant Antibody (CBT2869) (V2LY-0625-LY2776)

Name: Mouse Anti-THPO Recombinant Antibody (CBT2869)
SKU: V2LY-0625-LY2776
Rating: 5 (1 reviews)

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Tested Data

Mouse Anti-THPO Recombinant Antibody (CBT2869) (V2LY-0625-LY2776) in WB

Mouse Anti-THPO Recombinant Antibody (CBT2869) (V2LY-0625-LY2776) in FC

Mouse Anti-THPO Recombinant Antibody (CBT2869) (V2LY-0625-LY2776) in ELISA

Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBT2869

Application

Immunogen

Purified recombinant fragment of human THPO expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
FC	1:200-1:400
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Thrombopoietin

Entrez Gene ID

7066

Function

Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

Biological Process

Biological Process cell population proliferationSource:InterPro
Biological Process cellular response to lipopolysaccharideSource:Ensembl
Biological Process megakaryocyte developmentSource:ARUK-UCL1 Publication
Biological Process megakaryocyte differentiationSource:UniProtKB1 Publication
Biological Process positive regulation of cell population proliferationSource:ARUK-UCL1 Publication
Biological Process positive regulation of ERK1 and ERK2 cascadeSource:UniProtKB
Biological Process positive regulation of hematopoietic stem cell proliferationSource:MGI1 Publication
Biological Process positive regulation of MAPK cascadeSource:ARUK-UCL1 Publication
Biological Process positive regulation of megakaryocyte differentiationSource:UniProtKB
Biological Process positive regulation of protein kinase B signalingSource:ARUK-UCL1 Publication
Biological Process positive regulation of protein phosphorylationSource:UniProtKB
Biological Process receptor signaling pathway via STATSource:ARUK-UCL1 Publication
Biological Process thrombopoietin-mediated signaling pathwaySource:ARUK-UCL1 Publication

Cellular Location

Secreted

Involvement in disease

Thrombocythemia 1 (THCYT1):
A myeloproliferative disorder characterized by excessive platelet production, resulting in increased numbers of circulating platelets. It can be associated with spontaneous hemorrhages and thrombotic episodes.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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