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Mouse Anti-THY1 Monoclonal Antibody (HIS51) (CBMAB-1637-YC)

Provided herein is a mouse monoclonal antibody against Rat THY1. The antibody, clone HIS51, can be used for immunoassay techniques, such as FC.
See all THY1 antibodies
Published Data
Fig.1 Flow cytometry detection of surface antigens on ADMSCs: after induction, the CD90+ cells were the highest populations of stem cells.
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Fig.2 Representative images and quantitative analysis results of apoptosis in rat models as illustrated by TUNEL staining.
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Fig.3 Immunofluorescence (green) of CD90 in cultured EPDCs.
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Fig.4 Schematic of tx administration to Tbx21RFP-CreERT2 mice (above) and flow cytometry (below) of splenic CD4 Thy1.1+ and Thy1.1− cells.
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Summary

Host Animal
Mouse
Specificity
Rat, Mouse
Clone
HIS51
Antibody Isotype
IgG2a
Application
FC

Basic Information

Immunogen
Rat bone marrow cells
Specificity
Rat, Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
THY1 Gene(Protein Coding) Thy-1 Cell Surface Antigen
Introduction
THY1 is a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins which is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. THY1 is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma.
Entrez Gene ID
Mouse21838
Rat24832
UniProt ID
MouseP01831
RatP01830
Alternative Names
T25; CD90; Thy-1; Thy1.1; Thy1.2; Thy-1.2
Function
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Biological Process
Biological Process angiogenesisSource:UniProtKB
Biological Process cell-cell adhesionSource:UniProtKB
Biological Process cell-cell signalingSource:UniProtKBBy Similarity
Biological Process cytoskeleton organizationSource:UniProtKB
Biological Process focal adhesion assemblySource:UniProtKB
Biological Process integrin-mediated signaling pathwaySource:UniProtKB1 Publication
Biological Process negative regulation of axonogenesisSource:UniProtKB
Biological Process negative regulation of cell migrationSource:UniProtKB
Biological Process negative regulation of neuron projection regenerationSource:UniProtKBBy Similarity
Biological Process negative regulation of protein kinase activitySource:UniProtKB
Biological Process negative regulation of protein tyrosine kinase activitySource:UniProtKB
Biological Process negative regulation of T cell receptor signaling pathwaySource:UniProtKB
Biological Process positive regulation of cellular extravasationSource:UniProtKB1 Publication
Biological Process positive regulation of focal adhesion assemblySource:UniProtKB1 Publication
Biological Process positive regulation of GTPase activitySource:UniProtKB
Biological Process positive regulation of heterotypic cell-cell adhesionSource:UniProtKB1 Publication
Biological Process positive regulation of release of sequestered calcium ion into cytosolSource:UniProtKB
Biological Process positive regulation of T cell activationSource:UniProtKB
Biological Process protein autophosphorylationSource:Ensembl
Biological Process receptor clusteringSource:UniProtKB
Biological Process regulation of cell-matrix adhesionSource:UniProtKB1 Publication
Biological Process regulation of Rho-dependent protein serine/threonine kinase activitySource:UniProtKBBy Similarity
Biological Process response to axon injurySource:Ensembl
Biological Process retinal cone cell developmentSource:UniProtKB
Biological Process T cell receptor signaling pathwaySource:UniProtKB
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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