Rabbit Anti-TIGIT Recombinant Antibody (CBR047F) (CBMAB-BT085LY)

Name: Rabbit Anti-TIGIT Recombinant Antibody (CBR047F)
SKU: CBMAB-BT085LY
Rating: 5 (1 reviews)

See all TIGIT antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

CBR047F

Application

WB, IHC, IHC-IF

Immunogen

aa 194-244 (C-term)

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

T cell immunoreceptor with Ig and ITIM domains

Introduction

This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]

Entrez Gene ID

201633

UniProt ID

Q495A1

Alternative Names

T Cell Immunoreceptor With Ig And ITIM Domains; V-Set And Immunoglobulin Domain-Containing Protein 9; V-Set And Transmembrane Domain-Containing Protein 3; T-Cell Immunoreceptor With Ig And ITIM Domains; VSIG9, VSTM3; VSIG9;

Function

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Biological Process

Biological Process negative regulation of interleukin-12 productionSource:UniProtKB1 Publication
Biological Process negative regulation of T cell activationSource:MGI1 Publication
Biological Process positive regulation of interleukin-10 productionSource:UniProtKB1 Publication

Cellular Location

Cell membrane

Topology

Extracellular: 22-141
Helical: 142-162
Cytoplasmic: 163-244

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Rabbit Anti-TIGIT Recombinant Antibody (CBR047F)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-TIGIT Recombinant Antibody (CBYJT-3140) (CAT#: CBMAB-T2411-YJ)

Mouse Anti-TIGIT Recombinant Antibody (CBT2084) (CAT#: V2LY-0625-LY1024)

Recombinant Mouse Anti-TIGIT Recombinant Antibody (13E7) (CAT#: CBMAB-XB1141-YC)

Mouse Anti-TIGIT Recombinant Antibody (CBYJT-3141) (CAT#: CBMAB-T2412-YJ)

Mouse Anti-Tigit Recombinant Antibody (CBYJT-3144) (CAT#: CBMAB-T2415-YJ)

Mouse Anti-TIGIT Recombinant Antibody (CBYJT-3142) (CAT#: CBMAB-T2413-YJ)

Mouse Anti-TIGIT Recombinant Antibody (AG177) (CAT#: V2LY-0524-LY54)

Rabbit Anti-TIGIT Recombinant Antibody (E6L7H) (CAT#: CBMAB-CP2771-LY)

Rat Anti-Tigit Recombinant Antibody (CBYJT-3145) (CAT#: CBMAB-T2416-YJ)

Mouse Anti-TIGIT Recombinant Antibody (CBYJT-3143) (CAT#: CBMAB-T2414-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry