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Mouse Anti-TLR5 Recombinant Antibody (CBYJT-3394) (CBMAB-T2705-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TLR5 (Toll Like Receptor 5). The antibody can be used for immunoassay techniques, such as ELISA, ICC, IHC, WB.
Host Species
Mouse
Application
ELISA, ICC, IHC, WB
Immunogen
Recombinant TLR5 (Asn46~Ala205) expressed in E. coli
Antibody Isotype
IgG
Specificity
Human
Cross Reactivity
Human
Clone
CBYJT-3394
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
TLR5 encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. TLR5 recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of it mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
Alternative Name
Toll Like Receptor 5; Toll/Interleukin-1 Receptor-Like Protein 3; Systemic Lupus Erythematosus Susceptibility 1; Toll-Like Receptor 5; TIL3; MELIOS; SLEB1; SLE1
Entrez Gene ID
UniProt ID
Cat CBMAB-T2705-YJ
Conjugates
Size
Price $
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