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Mouse Anti-TLX3 Recombinant Antibody (5D2) (CBMAB-A9207-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
5D2
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
TLX3 (NP_066305, 192 a.a. ~ 291 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
T-cell leukemia homeobox 3
Introduction
RNX (HOX11L2, TLX3) belongs to a family of orphan homeobox genes that encode DNA-binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine-47 replacing cytosine in the highly conserved homeodomain (Dear et al., 1993 [PubMed 8099440]).[supplied by OMIM
Entrez Gene ID
30012
UniProt ID
O43711
Alternative Names
HOX11L2; MGC29804; RNX
Biological Process
Biological Process animal organ developmentSource:GO_Central1 Publication
Biological Process central nervous system developmentSource:Ensembl
Biological Process GABAergic neuron differentiationSource:Ensembl
Biological Process negative regulation of neuron differentiationSource:Ensembl
Biological Process neuron fate specificationSource:Ensembl
Biological Process neuron migrationSource:Ensembl
Biological Process regulation of respiratory gaseous exchange by nervous system processSource:Ensembl
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Biological Process respiratory gaseous exchange by respiratory systemSource:Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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