Mouse Anti-TLX3 Recombinant Antibody (CBYJT-3443) (CBMAB-T2765-YJ)

Name: Mouse Anti-TLX3 Recombinant Antibody (CBYJT-3443)
SKU: CBMAB-T2765-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-3443

Application

WB, S-ELISA, ELISA

Immunogen

TLX3 (NP_066305, 192 a.a. ~ 291 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 192-291

More Infomation

Target

Full Name

T-cell leukemia homeobox 3

Introduction

TLX3 is an orphan homeobox protein that encodes a DNA-binding nuclear transcription factor. A translocation [t(5; 14)(q35; q32)] involving this gene is associated with T-cell acute lymphoblastic leukemia (T-ALL) in children and young adults.

Entrez Gene ID

30012

UniProt ID

O43711

Alternative Names

T Cell Leukemia Homeobox 3; T-Cell Leukemia Homeobox 3; Homeobox Protein Hox-11L2; Homeo Box 11-Like 2; HOX11L2; T-Cell Leukemia Homeobox Protein 3; T-Cell Leukemia, Homeobox 3; RNX

Biological Process

Biological Process animal organ developmentSource:GO_Central1 Publication
Biological Process central nervous system developmentSource:Ensembl
Biological Process GABAergic neuron differentiationSource:Ensembl
Biological Process negative regulation of neuron differentiationSource:Ensembl
Biological Process neuron fate specificationSource:Ensembl
Biological Process neuron migrationSource:Ensembl
Biological Process regulation of respiratory gaseous exchange by nervous system processSource:Ensembl
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Biological Process respiratory gaseous exchange by respiratory systemSource:Ensembl

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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