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Mouse Anti-TLX3 Recombinant Antibody (CBYJT-3441) (CBMAB-T2763-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TLX3 (T Cell Leukemia Homeobox 3). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TLX3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3441
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa192-292 from human TLX3 (NP_066305) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 192-292

Target

Full Name
T-cell leukemia homeobox 3
Introduction
TLX3 is an orphan homeobox protein that encodes a DNA-binding nuclear transcription factor. A translocation [t(5; 14)(q35; q32)] involving this gene is associated with T-cell acute lymphoblastic leukemia (T-ALL) in children and young adults.
Entrez Gene ID
UniProt ID
Alternative Names
T Cell Leukemia Homeobox 3; T-Cell Leukemia Homeobox 3; Homeobox Protein Hox-11L2; Homeo Box 11-Like 2; HOX11L2; T-Cell Leukemia Homeobox Protein 3; T-Cell Leukemia, Homeobox 3; RNX
Biological Process
Biological Process animal organ developmentSource:GO_Central1 Publication
Biological Process central nervous system developmentSource:Ensembl
Biological Process GABAergic neuron differentiationSource:Ensembl
Biological Process negative regulation of neuron differentiationSource:Ensembl
Biological Process neuron fate specificationSource:Ensembl
Biological Process neuron migrationSource:Ensembl
Biological Process regulation of respiratory gaseous exchange by nervous system processSource:Ensembl
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Biological Process respiratory gaseous exchange by respiratory systemSource:Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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