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Mouse Anti-TM4SF4 Recombinant Antibody (4E6) (CBMAB-A9208-LY)

The product is antibody recognizes TM4SF4. The antibody 4E6 immunoassay techniques such as: WB, ELISA.
See all TM4SF4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4E6
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
TM4SF4 (NP_004608.1, 1 a.a. ~ 202 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
transmembrane 4 L six family member 4
Introduction
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell proliferation. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]
Entrez Gene ID
7104
UniProt ID
P48230
Alternative Names
FLJ31015; ILTMP; il-TMP
Function
Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.
Biological Process
Tissue regeneration
Cellular Location
Membrane
Topology
Cytoplasmic: 1-9
Helical: 10-30
Extracellular: 31-49
Helical: 50-70
Cytoplasmic: 71-93
Helical: 94-114
Extracellular: 115-158
Helical: 159-179
Cytoplasmic: 180-202
PTM
N-glycosylated. Glycosylation is required for the growth inhibitory effect.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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