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Mouse Anti-TM4SF4 Recombinant Antibody (CBYJT-3450) (CBMAB-T2772-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3450
Antibody Isotype
IgG1
Application
FC, CyTOF

Basic Information

Immunogen
NS0 mouse myeloma cell line transfected with human TM4SF4, Accession # P48230
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
transmembrane 4 L six family member 4
Introduction
TM4SF4 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It mediate signal transduction events that function in the regulation of cell development, activation, growth and motility. TM4SF4 is a cell surface glycoprotein that can regulate cell proliferation.
Entrez Gene ID
7104
UniProt ID
P48230
Alternative Names
Transmembrane 4 L Six Family Member 4; Intestine And Liver Tetraspan Membrane Protein; Transmembrane 4 Superfamily Member 4; Il-TMP; ILTMP; Intestinal And Liver (Il) Tetraspan Membrane Protein; Transmembrane 4 L6 Family Member 4
Function
Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.
Biological Process
Tissue regeneration
Cellular Location
Membrane
Topology
Cytoplasmic: 1-9
Helical: 10-30
Extracellular: 31-49
Helical: 50-70
Cytoplasmic: 71-93
Helical: 94-114
Extracellular: 115-158
Helical: 159-179
Cytoplasmic: 180-202
PTM
N-glycosylated. Glycosylation is required for the growth inhibitory effect.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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