TM4SF4

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell proliferation. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]
Full Name
transmembrane 4 L six family member 4
Function
Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.
Biological Process
Tissue regeneration
Cellular Location
Membrane
Topology
Cytoplasmic: 1-9
Helical: 10-30
Extracellular: 31-49
Helical: 50-70
Cytoplasmic: 71-93
Helical: 94-114
Extracellular: 115-158
Helical: 159-179
Cytoplasmic: 180-202
PTM
N-glycosylated. Glycosylation is required for the growth inhibitory effect.
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Anti-TM4SF4 antibodies

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Mouse Anti-TM4SF4 Recombinant Antibody (4E6) (CBMAB-A9208-LY)

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Target: TM4SF4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4E6
Application*: WB, E
Datasheet SDS

Mouse Anti-TM4SF4 Recombinant Antibody (CBYJT-3450) (CBMAB-T2772-YJ)

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Target: TM4SF4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3450
Application*: F, MC
Datasheet SDS

Mouse Anti-TM4SF4 Recombinant Antibody (CBYJT-3449) (CBMAB-T2771-YJ)

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Target: TM4SF4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-3449
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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