Mouse Anti-TMEM119 Recombinant Antibody (CBT3224) (V2LY-0625-LY1893)
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Basic Information
| Application | Note |
| WB | 1:500-1:2,000 |
| IHC-P | 1:200-1:1,000 |
| FC | 1:200-1:400 |
| ELISA | 1:10,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Up-regulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity).
Biological Process endochondral ossificationSource:ARUK-UCL
Biological Process negative regulation of bone resorptionSource:ARUK-UCL
Biological Process negative regulation of myotube differentiationSource:ARUK-UCL
Biological Process osteoblast differentiationSource:Ensembl
Biological Process positive regulation of bone developmentSource:UniProtKB
Biological Process positive regulation of bone mineralizationSource:UniProtKB1 Publication
Biological Process positive regulation of gene expressionSource:ARUK-UCL
Biological Process positive regulation of osteoblast differentiationSource:UniProtKB1 Publication
Biological Process positive regulation of osteoblast proliferationSource:UniProtKB1 Publication
Biological Process positive regulation of protein phosphorylationSource:ARUK-UCL
Biological Process spermatid differentiationSource:UniProtKB
Biological Process spermatogenesisSource:UniProtKB
Cytoplasm
Endoplasmic reticulum membrane
Helical: 97-117
Cytoplasmic: 118-283
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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