Mouse Anti-TMIGD2 Recombinant Antibody (CBYJT-3534) (CBMAB-T2859-YJ)

Name: Mouse Anti-TMIGD2 Recombinant Antibody (CBYJT-3534)
SKU: CBMAB-T2859-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-3534

Application

FC, IHC, CyTOF

Immunogen

HEK293 human embryonic kidney cell line-derived human TMIGD2/CD28H, Met1-Gly150, Accession # Q96BF3

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-150

More Infomation

Target

Full Name

Transmembrane And Immunoglobulin Domain Containing 2

Introduction

TMIGD2 (Transmembrane And Immunoglobulin Domain Containing 2) is a Protein Coding gene. Among its related pathways are T Cell Co-Signaling Pathway: Ligand-Receptor Interactions. Gene Ontology (GO) annotations related to TMIGD2 include coreceptor activity.

Entrez Gene ID

126259

UniProt ID

Q96BF3

Alternative Names

Transmembrane And Immunoglobulin Domain Containing 2; Immunoglobulin And Proline-Rich Receptor 1; CD28 Homologue; CD28 Homolog; IGPR-1; CD28H; IGPR1

Function

Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.

Biological Process

Biological Process immune responseSource:GO_Central1 Publication
Biological Process positive regulation of activated T cell proliferationSource:UniProtKB1 Publication
Biological Process positive regulation of angiogenesisSource:CACAO1 Publication
Biological Process positive regulation of cytokine productionSource:UniProtKB1 Publication
Biological Process T cell costimulationSource:UniProtKB1 Publication

Cellular Location

Cell membrane

Topology

Extracellular: 23-150
Helical: 151-171
Cytoplasmic: 172-282

PTM

N-glycosylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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