Human Recombinant TMIGD2 protein, ECD, Biotin Conjugated, His & AVI Tag (V2LY-0526-LY2767)

Name: Human Recombinant TMIGD2 protein, ECD, Biotin Conjugated, His & AVI Tag
SKU: V2LY-0526-LY2767
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Human

Tag

His & AVI Tag

Protein Construction

This product is Human Recombinant TMIGD2 protein, ECD, Biotin Conjugated, His & AVI Tag consist of Amino Acid: 1-150 and predicts a molecular mass of 17.3 kDa.

Molecule Mass

17.3 kDa

Protein Domain

ECD

Verified

HPLC

Conjugates

Biotin

Sequence

Amino Acid: 1-150

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥95% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC.

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Transmembrane And Immunoglobulin Domain Containing 2

Function

Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.

Biological Process

Biological Process immune responseSource:GO_Central1 Publication
Biological Process positive regulation of activated T cell proliferationSource:UniProtKB1 Publication
Biological Process positive regulation of angiogenesisSource:CACAO1 Publication
Biological Process positive regulation of cytokine productionSource:UniProtKB1 Publication
Biological Process T cell costimulationSource:UniProtKB1 Publication

Cellular Location

Cell membrane

Topology

Extracellular: 23-150
Helical: 151-171
Cytoplasmic: 172-282

PTM

N-glycosylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant TMIGD2 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY2766)

Human Recombinant TMIGD2 protein, His Tag (CAT#: V2LY-0526-LY2768)

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Human Recombinant TMIGD2 protein, His Tag (CAT#: V2LY-0526-LY2768)

Human Recombinant TMIGD2 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY2766)

Mouse Anti-TMIGD2 Recombinant Antibody (CBYJT-3537) (CAT#: CBMAB-T2862-YJ)

Mouse Anti-TMIGD2 Recombinant Antibody (CBYJT-3535) (CAT#: CBMAB-T2860-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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