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Rabbit Anti-TNFRSF10D Recombinant Antibody (D13H4) (CBMAB-CP2849-LY)

The product is antibody recognizes DcR2. The antibody D13H4 immunoassay techniques such as: WB,IP.
See all TNFRSF10D antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Monkey
Clone
D13H4
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly270 of human DcR2 protein.
Specificity
Human, Monkey
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TNFRSF10D Gene(Protein Coding)


TNF Receptor Superfamily Member 10d
Entrez Gene ID
Human8793
Monkey716901
UniProt ID
HumanQ9UBN6
MonkeyF6TP00
Function
Receptor for the cytotoxic ligand TRAIL (PubMed:9430226).
Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis (PubMed:9537512).
Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway (PubMed:9382840, PubMed:9430226).
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:ProtInc1 Publication
Biological Process signal transduction Source:ProtInc1 Publication
Cellular Location
Membrane
Topology
Extracellular: 56-211
Helical: 212-232
Cytoplasmic: 233-386
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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