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TNFRSF10D

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]

Full Name

TNFRSF10D Gene(Protein Coding)

TNF Receptor Superfamily Member 10d

Function

Receptor for the cytotoxic ligand TRAIL (PubMed:9430226).
Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis (PubMed:9537512).
Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway (PubMed:9382840, PubMed:9430226).

Biological Process

Biological Process apoptotic process Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:ProtInc1 Publication
Biological Process signal transduction Source:ProtInc1 Publication

Cellular Location

Membrane

Topology

Extracellular: 56-211
Helical: 212-232
Cytoplasmic: 233-386

Anti-TNFRSF10D antibodies

Rabbit Anti-TNFRSF10D Recombinant Antibody (CBYJT-3671) (CBMAB-T3044-YJ)

SDS

Target: TNFRSF10D

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-3671

Application*: P

Mouse Anti-TNFRSF10D Recombinant Antibody (CBYJT-3672) (CBMAB-T3045-YJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3672

Application*: WB, F, N, MC, EC

Rabbit Anti-TNFRSF10D Recombinant Antibody (CBYJT-3673) (CBMAB-T3046-YJ)

SDS

Target: TNFRSF10D

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-3673

Application*: E

Mouse Anti-TNFRSF10D Recombinant Antibody (CBYJT-3674) (CBMAB-T3047-YJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3674

Application*: WB, F, N

Mouse Anti-TNFRSF10D Recombinant Antibody (CBYJT-3675) (CBMAB-T3049-YJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3675

Application*: F, IP, WB

Mouse Anti-TNFRSF10D Recombinant Antibody (B-R27) (CBMAB-T3050-YJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: B-R27

Application*: F

Mouse Anti-TNFRSF10D Recombinant Antibody (CBYJT-3676) (CBMAB-T3051-YJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3676

Application*: E

Mouse Anti-TNFRSF10D Recombinant Antibody (HS402) (CBMAB-T3052-YJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: HS402

Application*: F, IC, IH, IP

Mouse Anti-TNFRSF10D Recombinant Antibody (CBYJT-3677) (CBMAB-T3053-YJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3677

Application*: WB, B, N

Mouse Anti-TNFRSF10D Recombinant Antibody (CBYJT-3678) (CBMAB-T3054-YJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3678

Application*: F, MC

Rabbit Anti-TNFRSF10D Recombinant Antibody (CBYJT-3679) (CBMAB-T3055-YJ)

SDS

Target: TNFRSF10D

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Monkey

Clone: CBYJT-3679

Application*: WB, IP

Rabbit Anti-TNFRSF10D Recombinant Antibody (D13H4) (CBMAB-CP2849-LY)

SDS

Target: TNFRSF10D

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Monkey

Clone: D13H4

Application*: WB, IP

Mouse Anti-TNFRSF10D Recombinant Antibody (B-P30) (CBMAB-D2313-YC)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: B-P30

Application*: WB, IP

Mouse Anti-TNFRSF10D Recombinant Antibody (TRAIL-R4-01) (CBMAB-D2314-YC)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: TRAIL-R4-01

Application*: F

Rabbit Anti-TNFRSF10D Recombinant Antibody (CBYCD-519) (CBMAB-D2315-YC)

SDS

Target: TNFRSF10D

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBYCD-519

Application*: WB, P, IC

Mouse Anti-TNFRSF10D Recombinant Antibody (CBWJC-2434) (CBMAB-C3476WJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJC-2434

Application*: F

Mouse Anti-TNFRSF10D Recombinant Antibody (CBWJC-4518) (CBMAB-C5911WJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBWJC-4518

Application*: E

Mouse Anti-TNFRSF10D Recombinant Antibody (CBWJC-4519) (CBMAB-C5912WJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJC-4519

Application*: IP, WB

Mouse Anti-TNFRSF10D Recombinant Antibody (CBWJC-4520) (CBMAB-C5913WJ)

SDS

Target: TNFRSF10D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJC-4520

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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