TNFRSF10D
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]
Full Name
TNFRSF10D Gene(Protein Coding)
TNF Receptor Superfamily Member 10d
TNF Receptor Superfamily Member 10d
Function
Receptor for the cytotoxic ligand TRAIL (PubMed:9430226).
Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis (PubMed:9537512).
Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway (PubMed:9382840, PubMed:9430226).
Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis (PubMed:9537512).
Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway (PubMed:9382840, PubMed:9430226).
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:ProtInc1 Publication
Biological Process signal transduction Source:ProtInc1 Publication
Biological Process negative regulation of apoptotic process Source:ProtInc1 Publication
Biological Process signal transduction Source:ProtInc1 Publication
Cellular Location
Membrane
Topology
Extracellular: 56-211
Helical: 212-232
Cytoplasmic: 233-386
Helical: 212-232
Cytoplasmic: 233-386
View more
Anti-TNFRSF10D antibodies
+ Filters
Loading...
CompareTarget: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4520
Application*: E
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4519
Application*: IP, WB
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-4518
Application*: E
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2434
Application*: F
Target: TNFRSF10D
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: CBYJT-3679
Application*: WB, IP
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3678
Application*: F, MC
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3677
Application*: WB, B, N
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HS402
Application*: F, IC, IH, IP
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3676
Application*: E
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-R27
Application*: F
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3675
Application*: F, IP, WB
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3674
Application*: WB, F, N
Target: TNFRSF10D
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3673
Application*: E
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3672
Application*: WB, F, N, MC, EC
Target: TNFRSF10D
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3671
Application*: P
Target: TNFRSF10D
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCD-519
Application*: WB, P, IC
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: TRAIL-R4-01
Application*: F
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-P30
Application*: WB, IP
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBT4040
Application*: WB
Target: TNFRSF10D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBT3197
Application*: WB
Target: TNFRSF10D
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: D13H4
Application*: WB, IP
More Infomation
Hot products 
-
Mouse Anti-CECR2 Recombinant Antibody (CBWJC-2465) (CBMAB-C3533WJ)
-
Mouse Anti-AKT1/AKT2/AKT3 (Phosphorylated T308, T309, T305) Recombinant Antibody (V2-443454) (PTM-CBMAB-0030YC)
-
Mouse Anti-COL12A1 Recombinant Antibody (CBYY-C3117) (CBMAB-C4560-YY)
-
Rat Anti-EMCN Recombinant Antibody (28) (CBMAB-E0280-FY)
-
Mouse Anti-A2M Recombinant Antibody (V2-178822) (CBMAB-A0036-YC)
-
Rat Anti-CD300A Recombinant Antibody (172224) (CBMAB-C0423-LY)
-
Mouse Anti-CD33 Recombinant Antibody (P67.6) (CBMAB-C10189-LY)
-
Mouse Anti-CAPZB Recombinant Antibody (CBYY-C0944) (CBMAB-C2381-YY)
-
Mouse Anti-ABCA3 Recombinant Antibody (V2-178911) (CBMAB-A0145-YC)
-
Mouse Anti-FOXA3 Recombinant Antibody (2A9) (CBMAB-0377-YC)
-
Mouse Anti-ALPL Antibody (B4-78) (CBMAB-1009CQ)
-
Mouse Anti-BLK Recombinant Antibody (CBYY-0618) (CBMAB-0621-YY)
-
Mouse Anti-2C TCR Recombinant Antibody (V2-1556) (CBMAB-0951-LY)
-
Rabbit Anti-ADRA1A Recombinant Antibody (V2-12532) (CBMAB-1022-CN)
-
Mouse Anti-ENPP1 Recombinant Antibody (CBFYE-0159) (CBMAB-E0375-FY)
-
Mouse Anti-BIRC3 Recombinant Antibody (16E63) (CBMAB-C3367-LY)
-
Mouse Anti-BAX Recombinant Antibody (CBYY-0216) (CBMAB-0217-YY)
-
Mouse Anti-DHFR Recombinant Antibody (D0821) (CBMAB-D0821-YC)
-
Mouse Anti-CD24 Recombinant Antibody (ALB9) (CBMAB-0176CQ)
-
Mouse Anti-ADAM12 Recombinant Antibody (V2-179752) (CBMAB-A1114-YC)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
Online Inquiry