Human TNFRSF10D ELISA Kit (V2LY-0626-LY32)

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Tested Data
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Basic Information

Sensitivity
0.058 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, Plasma, cell culture supernates, Ascites, tissue homogenates or other biological fluids
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Components
  • Standard Solution: 0.5ml x1
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard Diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop Solution: 6ml x1
  • Substrate Solution A: 6ml x1
  • Substrate Solution B: 6ml x1
  • Wash Buffer Concentrate (25x): 20ml x1
  • Biotinylated Antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
TNFRSF10D Gene(Protein Coding)


TNF Receptor Superfamily Member 10d
Function
Receptor for the cytotoxic ligand TRAIL (PubMed:9430226).
Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis (PubMed:9537512).
Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway (PubMed:9382840, PubMed:9430226).
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:ProtInc1 Publication
Biological Process signal transduction Source:ProtInc1 Publication
Cellular Location
Membrane
Topology
Extracellular: 56-211
Helical: 212-232
Cytoplasmic: 233-386
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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