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Mouse Anti-TNFRSF10D Recombinant Antibody (CBT4040) (V2LY-0625-LY1062)


See all TNFRSF10D antibodies
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Tested Data
Mouse Anti-TNFRSF10D Recombinant Antibody (CBT4040) (V2LY-0625-LY1062) in ELISA
Mouse Anti-TNFRSF10D Recombinant Antibody (CBT4040) (V2LY-0625-LY1062) in ELISA
Mouse Anti-TNFRSF10D Recombinant Antibody (CBT4040) (V2LY-0625-LY1062) in WB
Mouse Anti-TNFRSF10D Recombinant Antibody (CBT4040) (V2LY-0625-LY1062) in WB
Mouse Anti-TNFRSF10D Recombinant Antibody (CBT4040) (V2LY-0625-LY1062) in WB
Mouse Anti-TNFRSF10D Recombinant Antibody (CBT4040) (V2LY-0625-LY1062) in WB
Mouse Anti-TNFRSF10D Recombinant Antibody (CBT4040) (V2LY-0625-LY1062) in WB
Mouse Anti-TNFRSF10D Recombinant Antibody (CBT4040) (V2LY-0625-LY1062) in WB

Summary

Host Animal
Mouse
Specificity
Human, Monkey
Clone
CBT4040
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Purified recombinant fragment of human TNFRSF10D (AA: extra 56-211) expressed in E. Coli.
Host Species
Mouse
Specificity
Human, Monkey
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TNFRSF10D Gene(Protein Coding)


TNF Receptor Superfamily Member 10d
Entrez Gene ID
8793
Function
Receptor for the cytotoxic ligand TRAIL (PubMed:9430226).
Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis (PubMed:9537512).
Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway (PubMed:9382840, PubMed:9430226).
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:ProtInc1 Publication
Biological Process signal transduction Source:ProtInc1 Publication
Cellular Location
Membrane
Topology
Extracellular: 56-211
Helical: 212-232
Cytoplasmic: 233-386
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For research use only. Not intended for any clinical use.

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