Rat Anti-Tnfrsf13c Recombinant Antibody (CBYJT-3736) (CBMAB-T3116-YJ)

Name: Rat Anti-Tnfrsf13c Recombinant Antibody (CBYJT-3736)
SKU: CBMAB-T3116-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

CBYJT-3736

Application

FC, FuncS

Immunogen

Y3 cells transfected with mouse BAFF-R

Specificity

Mouse

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

TNFRSF13C Gene(Protein Coding) TNF Receptor Superfamily Member 13C

Introduction

Tnfrsf13c is a B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. It promotes the survival of mature B-cells and the B-cell response.

Entrez Gene ID

72049

UniProt ID

Q9D8D0

Alternative Names

Bcmd; Baffr; Bcmd1; BAFF-R; Bcmd-1; Lvis22; 2010006P15Rik

Function

B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.

Biological Process

Biological Process adaptive immune response Source:UniProtKB-KW
Biological Process B cell costimulation Source:GO_Central1 Publication
Biological Process positive regulation of B cell proliferation Source:GO_Central1 Publication
Biological Process positive regulation of T cell proliferation Source:GO_Central1 Publication
Biological Process T cell costimulation Source:GO_Central1 Publication
Biological Process tumor necrosis factor-mediated signaling pathway Source:InterPro

Cellular Location

Membrane

Involvement in disease

Immunodeficiency, common variable, 4 (CVID4):
A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low.

Topology

Extracellular: 1-78
Helical: 79-99
Cytoplasmic: 100-184

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

TNFRSF13C Matched Antibody Pair (1219) (CAT#: APMAB-1219LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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