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Human Anti-TNFRSF1B Recombinant Antibody (CBXC-0756) (CBMAB-C1870-CQ)

This product is a recombinant human antibody that recognizes TNFRSF1B. The antibody CBXC-0756 can be used for immunoassay techniques such as: FC.
Host Species
Human
Application
FC
Antibody Isotype
IgG1
Specificity
Mouse
Clone
CBXC-0756
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Alternative Name
TNF Receptor Superfamily Member 1B; Tumor Necrosis Factor Receptor Type II; Tumor Necrosis Factor Receptor 2; P80 TNF-Alpha Receptor; TNF-RII; TNF-R2; TNFR2; TNFBR; P75; Tumor Necrosis Factor Receptor Superfamily, Member 1B; Tumor Necrosis Factor Receptor Superfamily Member 1B; Tumor Necrosis Factor Binding Protein 2; Tumor Necrosis Factor Beta Receptor;
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-C1870-CQ
Conjugates
Size
Price $
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Second antibody and isotype control