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Mouse Anti-TNFRSF9 Recombinant Antibody (CBYJT-3881) (CBMAB-T3276-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TNFRSF9 (TNF Receptor Superfamily Member 9). The antibody can be used for immunoassay techniques, such as FC.
See all TNFRSF9 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3881
Antibody Isotype
IgG2b
Application
FC

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS
Preservative
0.1% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TNFRSF9 Gene(Protein Coding) TNF Receptor Superfamily Member 9
Introduction
TNFRSF9 is a member of the TNF-receptor superfamily. It contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of it is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to It and transduce the signals leading to activation of NF-kappaB.
Entrez Gene ID
3604
UniProt ID
Q07011
Alternative Names
TNF Receptor Superfamily Member 9; T-Cell Antigen 4-1BB Homolog; 4-1BB Ligand Receptor; CD137 Antigen; CDw137; CD137; ILA; Interleukin-Activated Receptor, Homolog Of Mouse Ly63; Tumor Necrosis Factor Receptor Superfamily, Member 9
Function
Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
Biological Process
Biological Process apoptotic process Source:ProtInc1 Publication
Biological Process negative regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process regulation of cell population proliferation Source:GO_Central1 Publication
Biological Process regulation of immature T cell proliferation in thymus Source:Ensembl
Cellular Location
Membrane
Topology
Extracellular: 24-186
Helical: 187-213
Cytoplasmic: 214-255
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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