Rat Anti-TNFSF9 Recombinant Antibody (MAB0875) (CBMAB-2111CQ)

Name: Rat Anti-TNFSF9 Recombinant Antibody (MAB0875)
SKU: CBMAB-2111CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

MAB0875

Application

Blocking, FC

Specificity

Mouse

Antibody Isotype

IgG2

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

TNFRSF9 Gene(Protein Coding) TNF Receptor Superfamily Member 9

Introduction

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation.

Entrez Gene ID

21950

UniProt ID

P41274

Alternative Names

CD137L; TNLG5A; 4-1BB-L

Function

Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

Biological Process

Biological Process apoptotic process Source:ProtInc1 Publication
Biological Process negative regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process regulation of cell population proliferation Source:GO_Central1 Publication
Biological Process regulation of immature T cell proliferation in thymus Source:Ensembl

Cellular Location

Membrane

Topology

Extracellular: 24-186
Helical: 187-213
Cytoplasmic: 214-255

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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