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Mouse Anti-TOMM22 Recombinant Antibody (4G4) (CBMAB-A9422-LY)

The product is antibody recognizes TOMM22. The antibody 4G4 immunoassay techniques such as: WB, ELISA.
See all TOMM22 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
4G4
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
TOMM22 (AAH09363, 1 a.a. ~ 142 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
translocase of outer mitochondrial membrane 22 homolog (yeast)
Introduction
The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion. [provided by RefSeq]
Entrez Gene ID
Human56993
Mouse223696
Rat300075
UniProt ID
HumanQ9NS69
MouseQ9CPQ3
RatQ75Q41
Alternative Names
1C9-2; MST065; MSTP065; TOM22
Function
Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore (PubMed:10982837).
Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases (By similarity).
Biological Process
Biological Process positive regulation of apoptotic process Source:Ensembl
Biological Process protein insertion into mitochondrial outer membrane Source:BHF-UCL1 Publication
Biological Process protein targeting to mitochondrion Source:HGNC-UCL1 Publication
Cellular Location
Mitochondrion outer membrane
Topology
Cytoplasmic: 2-83
Helical: 84-103
Mitochondrial intermembrane: 104-142
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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