TOMM22

The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion. [provided by RefSeq]
Full Name
translocase of outer mitochondrial membrane 22 homolog (yeast)
Function
Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore (PubMed:10982837).
Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases (By similarity).
Biological Process
Biological Process positive regulation of apoptotic process Source:Ensembl
Biological Process protein insertion into mitochondrial outer membrane Source:BHF-UCL1 Publication
Biological Process protein targeting to mitochondrion Source:HGNC-UCL1 Publication
Cellular Location
Mitochondrion outer membrane
Topology
Cytoplasmic: 2-83
Helical: 84-103
Mitochondrial intermembrane: 104-142
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Anti-TOMM22 antibodies

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Mouse Anti-TOMM22 Recombinant Antibody (4G4) (CBMAB-A9422-LY)

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Target: TOMM22
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 4G4
Application*: WB, E
Datasheet SDS

Mouse Anti-TOMM22 Recombinant Antibody (CBYJT-4175) (CBMAB-T3628-YJ)

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Target: TOMM22
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYJT-4175
Application*: E, IF, P, WB
Datasheet SDS

Mouse Anti-TOMM22 Recombinant Antibody (CBYJT-4174) (CBMAB-T3627-YJ)

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Target: TOMM22
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYJT-4174
Application*: E, WB, IH, IF
Datasheet SDS

Mouse Anti-TOMM22 Recombinant Antibody (CBYJT-4173) (CBMAB-T3626-YJ)

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Target: TOMM22
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBYJT-4173
Application*: EM, IC, IF, WB
Datasheet SDS

Rabbit Anti-TOMM22 Recombinant Antibody (
7C11) (V2LY-0725-LY1153)

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Target: TOMM22
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 7C11
Application*: E, WB, IH
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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