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Mouse Anti-TOMM22 Recombinant Antibody (CBYJT-4174) (CBMAB-T3627-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TOMM22 (Translocase Of Outer Mitochondrial Membrane 22). The antibody can be used for immunoassay techniques, such as ELISA, WB, IHC, IF.
See all TOMM22 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYJT-4174
Antibody Isotype
IgG2a, κ
Application
ELISA, WB, IHC, IF

Basic Information

Immunogen
Recognizes human TOMM22. Species Crossreactivity: mouse and rat
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
translocase of outer mitochondrial membrane 22 homolog (yeast)
Introduction
TOMM22 is an integral membrane protein of the mitochondrial outer membrane. TOMM22 interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion.
Entrez Gene ID
Human56993
Mouse223696
Rat300075
UniProt ID
HumanQ9NS69
MouseQ9CPQ3
RatQ75Q41
Alternative Names
Translocase Of Outer Mitochondrial Membrane 22; Translocase Of Outer Membrane 22 KDa Subunit Homolog; 1C9-2; TOM22; Translocase Of Outer Mitochondrial Membrane 22 Homolog (Yeast); Translocase Of Outer Mitochondrial Membrane 22 Homolog
Function
Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore (PubMed:10982837).
Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases (By similarity).
Biological Process
Biological Process positive regulation of apoptotic process Source:Ensembl
Biological Process protein insertion into mitochondrial outer membrane Source:BHF-UCL1 Publication
Biological Process protein targeting to mitochondrion Source:HGNC-UCL1 Publication
Cellular Location
Mitochondrion outer membrane
Topology
Cytoplasmic: 2-83
Helical: 84-103
Mitochondrial intermembrane: 104-142
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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