Sign in or Register   Sign in or Register
  |  

Mouse Anti-TPSB2 Recombinant Antibody (CBYJT-4416) (CBMAB-T3910-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TPSB2 (Tryptase Beta 2 (Gene/Pseudogene)). The antibody can be used for immunoassay techniques, such as WB, IP, Neut.
See all TPSB2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4416
Antibody Isotype
IgG1
Application
WB, IP, Neut

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Tryptase beta-2/TPSB2, Ile31-Pro275, Accession # AAD13876
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 31-275

Target

Full Name
Tryptase Beta 2
Introduction
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to function in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of TPSB2 exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Entrez Gene ID
UniProt ID
Alternative Names
Tryptase Beta 2 (Gene/Pseudogene); EC 3.4.21.59; TPS2; Testicular Tissue Protein Li 163; Mast Cell Tryptase Beta III; Mast Cell Tryptase Beta II; Tryptase Beta III; Tryptase Beta II
Function
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.
Biological Process
Biological Process proteolysis Source:ComplexPortal1 Publication
Cellular Location
Secreted
Released from the secretory granules upon mast cell activation.
Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Mouse Anti-TPSB2 Recombinant Antibody (CBYJT-4416)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare