TPSB2
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Tpsb2 has an immunoprotective role during bacterial infection. Tpsb2 is required to efficiently combat K.pneumoniae infection.
Full Name
Tryptase Beta 2
Function
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.
Biological Process
Biological Process proteolysis Source:ComplexPortal1 Publication
Cellular Location
Secreted
Released from the secretory granules upon mast cell activation.
Released from the secretory granules upon mast cell activation.
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Anti-TPSB2 antibodies
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Target: Tpsb2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYJT-4419
Application*: E, IP, N
Target: Tpsb2
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYJT-4418
Application*: IP, WB
Target: TPSB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4417
Application*: C, P
Target: TPSB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4416
Application*: WB, IP, N
Target: TPSB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4415
Application*: WB, IP
Target: TPSB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4414
Application*: E
Target: TPSB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4413
Application*: E
Target: TPSB2
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBFYM-3164
Application*: WB, IP
Target: Tpsb2
Sensitivity: 0.015 ng/mL
Detection Range: 0.03-9 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: Tpsb2
Sensitivity: 0.017 ng/mL
Detection Range: 0.05-10 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Rat
Assay Type: Sandwich
Reactivity: Rat
Target: TPSB2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: 9H6
Application*: E, WB, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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