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Mouse Anti-TPT1 Recombinant Antibody (3C7) (CBMAB-A9467-LY)

The product is antibody recognizes TPT1. The antibody 3C7 immunoassay techniques such as: WB, ELISA.
See all TPT1 antibodies
Published Data
Fig.1 TCTP binds to VHL and competes with HIF1α.
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Fig.2 Stable TCTP knockdown decreased the endogenous HIF1α protein levels.
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Fig.3 Western blot analysis confirmed the differentially expressed proteins in ovaries among the domestic strain, wild strain, and their F1.
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Fig.4 Subcellular localization of TCTP in the granulosa and cumulus cells of the mouse follicles.
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Fig.5 TCTP regulates autophagy through the AMPK pathway.
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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
3C7
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
TPT1 (AAH22436, 35 a.a. ~ 138 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TPT1 Gene(Protein Coding) Tumor Protein, Translationally-Controlled 1
Entrez Gene ID
Human7178
Mouse22070
Rat116646
UniProt ID
HumanP13693
MouseP63028
RatP63029
Alternative Names
FLJ27337; HRF; TCTP; p02
Function
Involved in calcium binding and microtubule stabilization.
Biological Process
Biological Process calcium ion transport Source:UniProtKB1 Publication
Biological Process cellular calcium ion homeostasis Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process negative regulation of ectoderm development Source:Ensembl
Biological Process negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source:MGI1 Publication
Biological Process regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process response to virus Source:UniProtKB1 Publication
Biological Process stem cell population maintenance Source:Ensembl
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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