Mouse Anti-TPT1 Recombinant Antibody (CBYJT-4435) (CBMAB-T3929-YJ)

Name: Mouse Anti-TPT1 Recombinant Antibody (CBYJT-4435)
SKU: CBMAB-T3929-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-4435

Application

ICC, IHC-P, ELISA, WB

Immunogen

The antibody is a mouse monoclonal antibody raised against TPT1. It has been selected for its ability to recognize TPT1 in immunohistochemical staining andwestern blotting

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4, 50% Glycerol

Preservative

0.02% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

TPT1 Gene(Protein Coding) Tumor Protein, Translationally-Controlled 1

Introduction

TPT1 is a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. TPT1 is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. TPT1 binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. TPT1 is known to function in carcinogenesis, and is upregulated in some cancer cells.

Entrez Gene ID

7178

UniProt ID

P13693

Alternative Names

Tumor Protein, Translationally-Controlled 1; Histamine-Releasing Factor; Fortilin; TCTP; P23; HRF; Translationally-Controlled Tumor Protein; P02

Function

Involved in calcium binding and microtubule stabilization.

Biological Process

Biological Process calcium ion transport Source:UniProtKB1 Publication
Biological Process cellular calcium ion homeostasis Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process negative regulation of ectoderm development Source:Ensembl
Biological Process negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source:MGI1 Publication
Biological Process regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process response to virus Source:UniProtKB1 Publication
Biological Process stem cell population maintenance Source:Ensembl

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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