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Mouse Anti-TPT1 Recombinant Antibody (CBYJT-4431) (CBMAB-T3925-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TPT1 (Tumor Protein, Translationally-Controlled 1). The antibody can be used for immunoassay techniques, such as ELISA, ICC, IHC, WB.
See all TPT1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4431
Antibody Isotype
IgG
Application
ELISA, ICC, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2, 50% Glycerol
Preservative
0.05% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TPT1 Gene(Protein Coding) Tumor Protein, Translationally-Controlled 1
Introduction
TPT1 is a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. TPT1 is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. TPT1 binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. TPT1 is known to function in carcinogenesis, and is upregulated in some cancer cells.
Entrez Gene ID
7178
UniProt ID
P13693
Alternative Names
Tumor Protein, Translationally-Controlled 1; Histamine-Releasing Factor; Fortilin; TCTP; P23; HRF; Translationally-Controlled Tumor Protein; P02
Function
Involved in calcium binding and microtubule stabilization.
Biological Process
Biological Process calcium ion transport Source:UniProtKB1 Publication
Biological Process cellular calcium ion homeostasis Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process negative regulation of ectoderm development Source:Ensembl
Biological Process negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source:MGI1 Publication
Biological Process regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process response to virus Source:UniProtKB1 Publication
Biological Process stem cell population maintenance Source:Ensembl
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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