Rabbit Anti-TRAP1 Recombinant Antibody (D3D7N) (CBMAB-CP1076-LY)

Name: Rabbit Anti-TRAP1 Recombinant Antibody (D3D7N)
SKU: CBMAB-CP1076-LY
Rating: 5 (1 reviews)

See all TRAP1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

D3D7N

Application

WB, IP, IF (ICC)

Immunogen

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro70 of human TRAP1/HSP75 protein.

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

100 µg/ml BSA, 50% glycerol

Preservative

0.02% sodium azide

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

TRAP1

Introduction

This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Entrez Gene ID

10131

UniProt ID

Q12931

Alternative Names

TNF Receptor Associated Protein 1; Tumor Necrosis Factor Type 1 Receptor-Associated Protein; TNFR-Associated Protein 1; TRAP-1; HSP 75; HSP75;

Function

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Biological Process

Biological Process chaperone-mediated protein folding Source:ParkinsonsUK-UCL1 Publication
Biological Process negative regulation of cellular respiration Source:UniProtKB1 Publication
Biological Process negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide Source:ParkinsonsUK-UCLBy Similarity
Biological Process negative regulation of reactive oxygen species biosynthetic process Source:ParkinsonsUK-UCL1 Publication
Biological Process protein folding Source:GO_Central1 Publication
Biological Process translational attenuation Source:CACAO1 Publication

Cellular Location

Mitochondrion
Mitochondrion inner membrane
Mitochondrion matrix

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Rabbit Anti-TRAP1 Recombinant Antibody (D3D7N)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-TRAP1 Recombinant Antibody (CBYJT-4552) (CAT#: CBMAB-T4063-YJ)

Rabbit Anti-TRAP1 Recombinant Antibody (CBYJT-4548) (CAT#: CBMAB-T4058-YJ)

Mouse Anti-TRAP1 Recombinant Antibody (CBYJT-4554) (CAT#: CBMAB-T4065-YJ)

Mouse Anti-TRAP1 Recombinant Antibody (CBYJT-4553) (CAT#: CBMAB-T4064-YJ)

Mouse Anti-TRAP1 Recombinant Antibody (CBYJT-4550) (CAT#: CBMAB-T4060-YJ)

Mouse Anti-TRAP1 Recombinant Antibody (CBYJT-4549) (CAT#: CBMAB-T4059-YJ)

Mouse Anti-TRAP1 Recombinant Antibody (CBFYH-2808) (CAT#: CBMAB-H3872-FY)

Mouse Anti-TRAP1 Recombinant Antibody (3H4-2H6) (CAT#: CBMAB-T4067-YJ)

Mouse Anti-TRAP1 Recombinant Antibody (CBYJT-4551) (CAT#: CBMAB-T4062-YJ)

Mouse Anti-TRAP1 Recombinant Antibody (9B6) (CAT#: CBMAB-T4066-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry