Human TRAP1 ELISA Kit (V2LY-0626-LY4651)

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Tested Data
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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.14 ng/mL
Detection Range
0.3-90 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
80.1 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
TRAP1
Function
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
Biological Process
Biological Process chaperone-mediated protein folding Source:ParkinsonsUK-UCL1 Publication
Biological Process negative regulation of cellular respiration Source:UniProtKB1 Publication
Biological Process negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide Source:ParkinsonsUK-UCLBy Similarity
Biological Process negative regulation of reactive oxygen species biosynthetic process Source:ParkinsonsUK-UCL1 Publication
Biological Process protein folding Source:GO_Central1 Publication
Biological Process translational attenuation Source:CACAO1 Publication
Cellular Location
Mitochondrion
Mitochondrion inner membrane
Mitochondrion matrix
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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