Sign in or Register   Sign in or Register
  |  

Mouse Anti-TRIM36 Recombinant Antibody (CBYJT-4759) (CBMAB-T4300-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TRIM36 (Tripartite Motif Containing 36). The antibody can be used for immunoassay techniques, such as ELISA, IF, WB.
See all TRIM36 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4759
Antibody Isotype
IgG1, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
TRIM36 (NP_061170, 391 a.a. ~ 499 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: TSFEDYVVNT SKQTELLGEL SFFSSGIDVP EINEEQSKVY NNALINWHHP EKDKADSYVL EYRKINRDDE MSWNEIEVCG TSKIIQDLEN SSTYAFRVRA YKGSICSPC
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 391-499

Target

Full Name
tripartite motif-containing 36
Introduction
TRIM36 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.
Entrez Gene ID
55521
UniProt ID
Q9NQ86
Alternative Names
Tripartite Motif Containing 36; Zinc-Binding Protein Rbcc728; RING Finger Protein 98; RING-Type E3 Ubiquitin Transferase TRIM36; Tripartite Motif-Containing Protein 36; Tripartite Motif Protein 36; RBCC728
Function
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation (PubMed:28087737).
May play a role in the acrosome reaction and fertilization.
Biological Process
Biological Process acrosome reaction Source:GO_Central1 Publication
Biological Process mitotic cytokinesis Source:UniProtKB1 Publication
Biological Process regulation of cell cycle Source:Ensembl
Biological Process regulation of microtubule cytoskeleton organization Source:UniProtKB1 Publication
Biological Process spindle organization Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Cytoplasmic vesicle, secretory vesicle, acrosome
Cytoplasm, cytoskeleton
Found in the acrosomal region of elongated spermatids and mature sperm.
Involvement in disease
Anencephaly 1 (ANPH1):
An extreme form of neural tube defect resulting in the absence of brain tissues, and death in utero or perinatally. Infants are born with intact spinal cords, cerebellums, and brainstems, but lack formation of neural structures above this level. The skull is only partially formed. ANPH1 inheritance is autosomal recessive.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TRIM36 Recombinant Antibody (CBYJT-4759)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare